#5633 USE OF HEPARIN GRAFTED DIALYZER (EVODIAL) FOR HEMODIALYSIS IN PATIENTS WITH HIGH RISK OF BLEEDING: A SINGLE CENTER EXPERIENCE

Abstract Background and Aims During hemodialysis exposure of the blood to dialysis membrane tubing system can activate cells promote clotting activation. So usually, some form anticoagulation, most frequently heparin, is used prevent coagulation. However, there are patients with increased risk for bleeding (patients active bleeding, major surgery in past 72 hours, severe trombocytopenia) where use heparin free regime mandatory. Evodial dialyzer (Gambro-Hospal, France) [1] contains a heparin-grafted aiming provide low thrombogenicity that be without or dose order reduce patients' risk. As high-quality evidence optimal choice anticoagulation these limited we wanted show our experience dialyzer. Method 12 months 106 sessions 59 were performed. Reasons using : hematological conditions, complications vascular access. Changes lines, any aditional interventions examined. Results Low unfractionated (1250 IE total) was 10 (9,4%) sessions, it added 15 (14%) more because problems In 4 (2,8%) had terminate clotting. Conclusion Heparin grafted dialyzers safely high bleeding. Although results worse than ones reported literature [2] regional citrate (RCA) used, reasonable alternative when RCA unavailable.